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Active B12 with L-5-MTHF

Active B12 with L-5-MTHF Lozenges by Seeking Health provide 800 mcg of pure non-racemic L-methylfolate in an easy-to deliver lozenge, along with two active “coenzyme” forms of vitamin B12. As “coenzyme” forms, methylcobalamin and adenosylcobalamin are the forms required by certain B12-dependent enzymes and reactions within the body. Similarly, L-5-methyltetrahydrofolate is considered an “active” form of folate - the body's most prevalent form of folate in plasma.* 

Vitamin B12 is crucial to the formation of healthy red blood cells, energy production, nervous system support, cognitive function, and homocysteine regulation. Folate as L-5-MTHF is also involved in homocysteine metabolism and efficiently supports methylation, DNA biosynthesis, and nervous system function.* 

  • HEALTHY MOOD AND FOCUS: Experience a supported healthy mood, focus, energy, and clarity. Note: This is a situational supplement; only take it when you feel that you need it. Other than those times, don’t take it, or as directed by your healthcare professional.*
  • LOZENGE: This easy-to-take and great-tasting lozenge isn’t your typical daily supplement. You should take it on an as-needed basis, or as directed by your healthcare professional. When you have a slight brain fog or feel unfocused, or fatigued, start with a small portion.*
Active B12 with L-5-MTHF


While folate and B12 are now commonly used to fortify cereals and grains, the synthetic forms of these important B vitamins used for fortification are often not well absorbed, nor added in amounts sufficient to meet the nutritional requirements of all individuals. Natural food sources of folate include liver, dark green leafy vegetables, avocado, peas and beans. Vitamin B12 is naturally present in seafood, shellfish, liver, eggs and dairy products. It may be harder for vegetarians and vegans to meet their daily needs for vitamin B12 from food sources without relying on supplements or fortified foods.* 

As each individual may have different needs for vitamin B12 and folate, the potent doses of these vitamins contained in Active B12 with L-5-MTHF may not be ideal for everyone. Working with a qualified healthcare professional is the best way determine the appropriate dose for your individual needs. The lozenges can be broken down into halves or quarters if a lower dose is desired. 

  • May help support cellular health
  • May help support the normal conversion of homocysteine to methionine
  • May help support cognitive health
  • May help support healthy energy levels

Take 1 lozenge daily, or as directed by your healthcare practitioner. Lozenge may be broken into smaller pieces if lower dosage is desired.



Serving Size: 1 Lozenge

Amount Per Serving
Folate ... 800mcg DFE
(as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt)
Vitamin B12 ... 1000mcg
(80% as methylcobalamin and 20% as adenosylcobalamin)

Other Ingredients: Xylitol, ascorbyl palmitate, natural cherry flavor, and silica.

Does not contain dairy, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMO

Suitable for vegetarians and vegans.
Warning: Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional before use if you are using antibiotics or other medications.

Disclaimer:The Pretty Hot Mess will not be held responsible for any claims or testimonials regarding medical efficacy of any of our products. The FDA (Food and Drug Administration) has not evaluated any of these statements, nor have the claims been confirmed by FDA-acknowledged research. Neither our staff nor our products are intended to diagnose, cure, prevent, or treat any disease or medical condition. Please consult your physician before including any of our products in your wellness plan.

This product has not been evaluated by the FDA. It is not intended to treat, cure, diagnose or prevent any disease.

Caution: Do not use if pregnant or nursing or if you have any diagnosed or undiagnosed health conditions. Do not use these products while taking any prescription or non-prescription drugs without consulting with your health care provider. Keep away from children. 

The Manufacturer and The Pretty Hot Mess, LLC cannot be held responsible, nor assume responsibility for any individual who consumes or misuses this product.This product should be used only as directed on the label or by your health care provider. This product is not intended to diagnose, treat, cure or prevent any disease. 

Please see additional Product Disclaimer here